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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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glnDUTP-GlnB uridylyltransferase, GlnD; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism. (885 aa)    
Predicted Functional Partners:
Psta_4136
PFAM: nitrogen regulatory protein P-II; KEGG: glnB; nitrogen regulatory protein PII; Belongs to the P(II) protein family.
 
 
 0.978
Psta_2981
PFAM: nitrogen regulatory protein P-II; KEGG: dvm:DvMF_0865 nitrogen regulatory protein P- II; Belongs to the P(II) protein family.
 
 
 0.960
Psta_3571
(Glutamate--ammonia-ligase) adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal tra [...]
 
   
 0.789
Psta_3570
PFAM: nitrogen regulatory protein P-II; KEGG: rce:RC1_1257 nitrogen regulatory protein P-II.
 
 
 
 0.710
Psta_1754
TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: sfu:Sfum_0576 glutamine synthetase, type I.
 
   
 0.617
Psta_3042
PFAM: CobB/CobQ domain protein glutamine amidotransferase; KEGG: scl:sce0213 hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolyzing).
   
    0.528
Psta_0199
PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: rma:Rmag_1018 glutamate synthase (ferredoxin).
     
 0.518
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
   
 0.474
Psta_2364
Flagellar L-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
  
     0.473
Psta_4489
PFAM: nitrogen regulatory protein P-II; KEGG: sat:SYN_02212 nitrogen regulatory protein PII; Belongs to the P(II) protein family.
 
 
 
 0.473
Your Current Organism:
Pirellula staleyi
NCBI taxonomy Id: 530564
Other names: P. staleyi DSM 6068, Pirellula staleyi ATCC 27377, Pirellula staleyi DSM 6068, Pirellula staleyi str. DSM 6068, Pirellula staleyi strain DSM 6068
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