Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Psta_4553TIGRFAM: 5-formyltetrahydrofolate cyclo-ligase; PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: dvu:DVU0366 5-formyltetrahydrofolate cyclo- ligase family protein; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (201 aa)    
Predicted Functional Partners:
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
  
 
 0.929
folD
Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
    
 0.927
Psta_2659
Methylenetetrahydrofolate dehydrogenase (NADP(+)); PFAM: Methylene-tetrahydromethanopterin dehydrogenase; KEGG: mch:Mchl_2133 methylenetetrahydrofolate dehydrogenase (NADP(+)).
     
  0.900
Psta_2390
TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; KEGG: sfu:Sfum_1671 FolC bifunctional protein; Belongs to the folylpolyglutamate synthase family.
    
 0.687
Psta_4552
TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.
       0.538
Psta_0005
PFAM: Rhomboid family protein; KEGG: sde:Sde_1225 regulatory proteins, IclR.
  
  
 0.522
Psta_2763
PFAM: Rhomboid family protein; KEGG: psa:PST_2418 rhomboid family protein.
  
  
 0.522
Psta_4751
PFAM: Rhomboid family protein; KEGG: rhomboid family protein.
  
  
 0.522
Psta_4554
PFAM: peptidase M24; KEGG: ppd:Ppro_2024 peptidase M24.
       0.491
pheT
KEGG: mxa:MXAN_3595 phenylalanyl-tRNA synthetase, beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
 
  
 0.446
Your Current Organism:
Pirellula staleyi
NCBI taxonomy Id: 530564
Other names: P. staleyi DSM 6068, Pirellula staleyi ATCC 27377, Pirellula staleyi DSM 6068, Pirellula staleyi str. DSM 6068, Pirellula staleyi strain DSM 6068
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