STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDD63205.1Citrate synthase; Belongs to the citrate synthase family. (372 aa)    
Predicted Functional Partners:
SDD08078.1
Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
 
 0.994
SDC16539.1
Aconitate hydratase.
  
 0.986
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.983
SDC11202.1
L-lactate dehydrogenase/malate dehydrogenase.
  
 0.978
Kgd
2-oxoglutarate decarboxylase.
  
 
 0.970
acsA
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.963
SDD13384.1
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase).
  
 0.962
SDD77826.1
acetyl-CoA synthetase.
  
 0.962
SDC49201.1
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
  
 0.961
SDC32377.1
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase).
  
 0.958
Your Current Organism:
Prauserella marina
NCBI taxonomy Id: 530584
Other names: CCTCC AA 208056, DSM 45268, Prauserella marina Wang et al. 2010, Prauserella sp. Ms498, strain MS498
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