STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FIC_004474-hydroxybutyrate coenzyme A transferase. (435 aa)    
Predicted Functional Partners:
FIC_02231
B12 binding domain / kinase domain / Methylmalonyl-CoA mutase.
  
  
 0.804
FIC_02232
B12 binding domain / kinase domain / Methylmalonyl-CoA mutase.
  
  
 0.804
FIC_00055
Methylmalonyl-CoA mutase.
  
  
 0.637
FIC_01989
Phenylacetic acid degradation protein PaaN, ring-opening aldehyde dehydrogenase.
  
  
 0.600
FIC_02253
NADP-dependent malic enzyme.
  
 
 0.579
FIC_01991
Citrate synthase (si); Belongs to the citrate synthase family.
  
 
 0.568
FIC_00448
Hypothetical protein.
       0.546
FIC_00946
3-hydroxyacyl-CoA dehydrogenase/Enoyl-CoA hydratase (isoleucine degradation).
  
 
 0.462
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
   
    0.454
sucC
Succinyl-CoA ligase [ADP-forming] beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
 
 0.440
Your Current Organism:
Flavobacteriaceae bacterium 351910
NCBI taxonomy Id: 531844
Other names: F. bacterium 3519-10, Flavobacteriaceae bacterium 3519-10
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