STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FIC_00642Coproporphyrinogen III oxidase, oxygen-independent; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (459 aa)    
Predicted Functional Partners:
hemE
Uroporphyrinogen III decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
 
 0.941
FIC_00146
Cytochrome c oxidase subunit CcoN; Belongs to the heme-copper respiratory oxidase family.
 
  
 0.939
FIC_00813
Hypothetical membrane protein, possible involvement in cytochrome functioning/assembly.
 
  
 0.926
FIC_00314
Hypothetical radical SAM family enzyme, NOT coproporphyrinogen III oxidase, oxygen-independent; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
  
  
 
0.920
FIC_00143
Type cbb3 cytochrome oxidase biogenesis protein CcoG, involved in Cu oxidation.
 
  
 0.803
FIC_00144
Cytochrome c oxidase subunit CcoP.
 
  
 0.741
FIC_00148
Type cbb3 cytochrome oxidase biogenesis protein CcoI; Copper-translocating P-type ATPase.
 
    0.702
FIC_00141
Uncharacterized protein; Heavy-metal-associated domain (N-terminus) and membrane-bounded cytochrome biogenesis cycZ-like domain, possible membrane copper tolerance protein.
 
   
 0.689
FIC_00142
Hypothetical protein.
 
    0.561
FIC_01712
Signal transduction histidine kinase.
     
 0.549
Your Current Organism:
Flavobacteriaceae bacterium 351910
NCBI taxonomy Id: 531844
Other names: F. bacterium 3519-10, Flavobacteriaceae bacterium 3519-10
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