STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FIC_00669Isocitrate lyase. (428 aa)    
Predicted Functional Partners:
FIC_00668
Malate synthase; Belongs to the malate synthase family.
 
 0.999
FIC_00162
Aconitate hydratase.
   
 
 0.927
FIC_01248
Hypothetical protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
     
 0.913
FIC_01886
4-Hydroxy-2-oxoglutarate aldolase.
     
 0.906
FIC_02253
NADP-dependent malic enzyme.
   
  
 0.806
FIC_00667
Helix-turn-helix domain protein.
 
   
 0.705
FIC_00670
Hypothetical protein.
       0.658
FIC_00946
3-hydroxyacyl-CoA dehydrogenase/Enoyl-CoA hydratase (isoleucine degradation).
  
  
 0.516
FIC_00671
Queuosine biosynthesis QueD, PTPS-I.
       0.473
FIC_00666
Competence protein.
       0.463
Your Current Organism:
Flavobacteriaceae bacterium 351910
NCBI taxonomy Id: 531844
Other names: F. bacterium 3519-10, Flavobacteriaceae bacterium 3519-10
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.