STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FIC_00697Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (335 aa)    
Predicted Functional Partners:
pdhA
Pyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 0.999
FIC_01401
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 0.997
FIC_01048
Dihydrolipoamide dehydrogenase of branched-chain alpha-keto acid dehydrogenase.
 0.990
FIC_01592
Dihydrolipoamide dehydrogenase of 2-oxoglutarate dehydrogenase.
 0.985
FIC_01488
Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex.
 0.976
FIC_02253
NADP-dependent malic enzyme.
  
 
 0.966
FIC_00781
Dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 0.961
FIC_02294
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.912
FIC_01046
Transketolase.
 
0.872
FIC_01383
2-oxoisovalerate dehydrogenase, E1 component, alpha and beta subunit.
 
0.865
Your Current Organism:
Flavobacteriaceae bacterium 351910
NCBI taxonomy Id: 531844
Other names: F. bacterium 3519-10, Flavobacteriaceae bacterium 3519-10
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