STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FIC_009443-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)    
Predicted Functional Partners:
FIC_00946
3-hydroxyacyl-CoA dehydrogenase/Enoyl-CoA hydratase (isoleucine degradation).
 
 0.999
FIC_00925
3-hydroxybutyryl-CoA dehydrogenase.
 0.971
FIC_01341
Glutaryl-CoA dehydrogenase.
  
 0.955
FIC_00098
Hydroxymethylglutaryl-CoA lyase.
  
 
 0.933
FIC_00965
Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
 
  
 
0.925
FIC_01598
acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
  
 
0.909
FIC_02280
Hydroxymethylglutaryl-CoA reductase; Belongs to the HMG-CoA reductase family.
 
  
 0.906
FIC_01006
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
  
 
 0.876
FIC_01007
prpE protein.
  
 
 0.876
FIC_01991
Citrate synthase (si); Belongs to the citrate synthase family.
  
 0.869
Your Current Organism:
Flavobacteriaceae bacterium 351910
NCBI taxonomy Id: 531844
Other names: F. bacterium 3519-10, Flavobacteriaceae bacterium 3519-10
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