STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FIC_00985Glycine dehydrogenase [decarboxylating] (glycine cleavage system P protein); Belongs to the GcvP family. (952 aa)    
Predicted Functional Partners:
gcvT
Aminomethyltransferase (glycine cleavage system T protein); The glycine cleavage system catalyzes the degradation of glycine.
 0.999
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 0.999
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
 
 
 0.998
purD
Phosphoribosylamine--glycine ligase; Belongs to the GARS family.
  
  
 0.981
FIC_00791
Phosphoribosylformylglycinamidine synthase, synthetase subunit.
  
  
 0.967
FIC_02394
Low-specificity L-threonine aldolase.
    
 0.958
FIC_01048
Dihydrolipoamide dehydrogenase of branched-chain alpha-keto acid dehydrogenase.
  
 
 0.951
FIC_01592
Dihydrolipoamide dehydrogenase of 2-oxoglutarate dehydrogenase.
  
 
 0.951
kbl
2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
  
 
 0.944
FIC_01299
2-amino-3-ketobutyrate coenzyme A ligase.
  
 
 0.944
Your Current Organism:
Flavobacteriaceae bacterium 351910
NCBI taxonomy Id: 531844
Other names: F. bacterium 3519-10, Flavobacteriaceae bacterium 3519-10
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.