STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FIC_01319NorM-like multidrug efflux protein. (466 aa)    
Predicted Functional Partners:
FIC_01320
Sigma-54 dependent transcriptional regulator/response regulator.
 
     0.719
FIC_01506
Phytoene synthase.
   
 
 0.715
FIC_00867
SSU ribosomal protein S1p; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
 
    0.699
FIC_00681
NAD-dependent glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
   
  
 0.681
FIC_01321
FIG018583: protein of unknown function; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
 
     0.575
FIC_02355
Small multidrug resistance protein.
  
  
 0.471
FIC_01446
Membrane protein, TerC family.
   
  
 0.461
FIC_00774
PAS/PAC domain protein.
 
 
 0.454
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.439
FIC_01712
Signal transduction histidine kinase.
  
 
 0.413
Your Current Organism:
Flavobacteriaceae bacterium 351910
NCBI taxonomy Id: 531844
Other names: F. bacterium 3519-10, Flavobacteriaceae bacterium 3519-10
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