STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadDNicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (194 aa)    
Predicted Functional Partners:
FIC_01801
Competence/damage-inducible protein CinA; Belongs to the CinA family.
  
 
 0.954
FIC_01788
NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
  
 
 0.934
pncB
Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.
  
 
 0.933
nadK
NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
 
 0.932
cobB
NAD-dependent protein deacetylase of SIR2 family; Belongs to the sirtuin family. Class III subfamily.
   
 0.929
FIC_02362
Quinolinate phosphoribosyltransferase (decarboxylating); Belongs to the NadC/ModD family.
    
 0.929
FIC_01058
Competence/damage-inducible protein CinA; Belongs to the CinA family.
  
 
 0.925
FIC_00164
Hypothetical protein.
     
 0.904
FIC_00475
5'-nucleotidase; Belongs to the 5'-nucleotidase family.
     
  0.900
surE
5'-nucleotidase surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
 0.900
Your Current Organism:
Flavobacteriaceae bacterium 351910
NCBI taxonomy Id: 531844
Other names: F. bacterium 3519-10, Flavobacteriaceae bacterium 3519-10
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