STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FIC_02280Hydroxymethylglutaryl-CoA reductase; Belongs to the HMG-CoA reductase family. (442 aa)    
Predicted Functional Partners:
FIC_00967
Mevalonate kinase.
 
 0.983
FIC_01598
acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
 
  
 0.914
FIC_00944
3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
 
  
 0.906
FIC_00965
Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
 
  
 0.890
FIC_02308
Hypothetical protein.
 
 
 0.868
FIC_01859
Diphosphomevalonate decarboxylase.
 
  
 0.862
FIC_02278
Protein of hypothetical function DUF423.
       0.773
FIC_02279
Hypothetical protein.
       0.773
menA
1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.
    
 
 0.710
FIC_01729
2-polyprenyl-6-methoxyphenol hydroxylase-likeFAD-dependent oxidoreductases.
   
  
 0.695
Your Current Organism:
Flavobacteriaceae bacterium 351910
NCBI taxonomy Id: 531844
Other names: F. bacterium 3519-10, Flavobacteriaceae bacterium 3519-10
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