node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FIC_00694 | FIC_00717 | FIC_00694 | FIC_00717 | CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Cystathionine beta-synthase. | 0.900 |
FIC_00694 | FIC_01300 | FIC_00694 | FIC_01300 | CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Cystathionine beta-synthase. | 0.900 |
FIC_00694 | FIC_01471 | FIC_00694 | FIC_01471 | CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.900 |
FIC_00694 | FIC_02094 | FIC_00694 | FIC_02094 | CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Serine acetyltransferase. | 0.800 |
FIC_00694 | FIC_02339 | FIC_00694 | FIC_02339 | CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Hexapeptide transferase family protein. | 0.800 |
FIC_00694 | glyA | FIC_00694 | FIC_00321 | CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.900 |
FIC_00694 | trpA | FIC_00694 | FIC_01491 | CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.900 |
FIC_00694 | trpB | FIC_00694 | FIC_01492 | CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.900 |
FIC_00717 | FIC_00694 | FIC_00717 | FIC_00694 | Cystathionine beta-synthase. | CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.900 |
FIC_00717 | FIC_01300 | FIC_00717 | FIC_01300 | Cystathionine beta-synthase. | Cystathionine beta-synthase. | 0.904 |
FIC_00717 | FIC_01471 | FIC_00717 | FIC_01471 | Cystathionine beta-synthase. | L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.906 |
FIC_00717 | FIC_02094 | FIC_00717 | FIC_02094 | Cystathionine beta-synthase. | Serine acetyltransferase. | 0.935 |
FIC_00717 | FIC_02095 | FIC_00717 | FIC_02095 | Cystathionine beta-synthase. | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.836 |
FIC_00717 | FIC_02339 | FIC_00717 | FIC_02339 | Cystathionine beta-synthase. | Hexapeptide transferase family protein. | 0.931 |
FIC_00717 | glyA | FIC_00717 | FIC_00321 | Cystathionine beta-synthase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.919 |
FIC_00717 | trpA | FIC_00717 | FIC_01491 | Cystathionine beta-synthase. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.909 |
FIC_00717 | trpB | FIC_00717 | FIC_01492 | Cystathionine beta-synthase. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.905 |
FIC_01300 | FIC_00694 | FIC_01300 | FIC_00694 | Cystathionine beta-synthase. | CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.900 |
FIC_01300 | FIC_00717 | FIC_01300 | FIC_00717 | Cystathionine beta-synthase. | Cystathionine beta-synthase. | 0.904 |
FIC_01300 | FIC_01471 | FIC_01300 | FIC_01471 | Cystathionine beta-synthase. | L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.906 |