node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CRD_00728 | CRD_02371 | CRD_00728 | CRD_02371 | Nitroreductase; Belongs to the flavin oxidoreductase frp family. | Conserved hypothetical protein CofD related; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | 0.457 |
CRD_01349 | CRD_02371 | CRD_01349 | CRD_02371 | Hypothetical protein. | Conserved hypothetical protein CofD related; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | 0.630 |
CRD_01837 | CRD_02371 | CRD_01837 | CRD_02371 | Radical SAM. | Conserved hypothetical protein CofD related; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | 0.536 |
CRD_01837 | cofH | CRD_01837 | CRD_01382 | Radical SAM. | Conserved hypothetical protein; Catalyzes the radical-mediated synthesis of 5-amino-5-(4- hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D- ribitylamino)uracil and L-tyrosine. | 0.994 |
CRD_02369 | CRD_02371 | CRD_02369 | CRD_02371 | Conserved hypothetical protein. | Conserved hypothetical protein CofD related; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | 0.497 |
CRD_02369 | CRD_02372 | CRD_02369 | CRD_02372 | Conserved hypothetical protein. | hetY (UPF0079 ATP-binding protein). | 0.465 |
CRD_02369 | ruvC | CRD_02369 | CRD_02370 | Conserved hypothetical protein. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.686 |
CRD_02371 | CRD_00728 | CRD_02371 | CRD_00728 | Conserved hypothetical protein CofD related; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | Nitroreductase; Belongs to the flavin oxidoreductase frp family. | 0.457 |
CRD_02371 | CRD_01349 | CRD_02371 | CRD_01349 | Conserved hypothetical protein CofD related; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | Hypothetical protein. | 0.630 |
CRD_02371 | CRD_01837 | CRD_02371 | CRD_01837 | Conserved hypothetical protein CofD related; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | Radical SAM. | 0.536 |
CRD_02371 | CRD_02369 | CRD_02371 | CRD_02369 | Conserved hypothetical protein CofD related; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | Conserved hypothetical protein. | 0.497 |
CRD_02371 | CRD_02372 | CRD_02371 | CRD_02372 | Conserved hypothetical protein CofD related; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | hetY (UPF0079 ATP-binding protein). | 0.749 |
CRD_02371 | CRD_02925 | CRD_02371 | CRD_02925 | Conserved hypothetical protein CofD related; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | conR (Cell envelope-related transcriptional attenuator). | 0.643 |
CRD_02371 | cofH | CRD_02371 | CRD_01382 | Conserved hypothetical protein CofD related; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | Conserved hypothetical protein; Catalyzes the radical-mediated synthesis of 5-amino-5-(4- hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D- ribitylamino)uracil and L-tyrosine. | 0.536 |
CRD_02371 | glmU | CRD_02371 | CRD_02138 | Conserved hypothetical protein CofD related; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | Bifunctional protein glmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.476 |
CRD_02371 | ruvC | CRD_02371 | CRD_02370 | Conserved hypothetical protein CofD related; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.583 |
CRD_02371 | thrB | CRD_02371 | CRD_02564 | Conserved hypothetical protein CofD related; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.480 |
CRD_02372 | CRD_02369 | CRD_02372 | CRD_02369 | hetY (UPF0079 ATP-binding protein). | Conserved hypothetical protein. | 0.465 |
CRD_02372 | CRD_02371 | CRD_02372 | CRD_02371 | hetY (UPF0079 ATP-binding protein). | Conserved hypothetical protein CofD related; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | 0.749 |
CRD_02372 | glmU | CRD_02372 | CRD_02138 | hetY (UPF0079 ATP-binding protein). | Bifunctional protein glmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.528 |