node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFN45523.1 | SFN60492.1 | SAMN05421579_10483 | SAMN05421579_11133 | Cysteine desulfurase. | Thioredoxin reductase (NADPH). | 0.660 |
SFN45523.1 | selD | SAMN05421579_10483 | SAMN05421579_1087 | Cysteine desulfurase. | Selenophosphate synthase; Synthesizes selenophosphate from selenide and ATP. | 0.556 |
SFN54340.1 | selD | SAMN05421579_1086 | SAMN05421579_1087 | Nitroreductase. | Selenophosphate synthase; Synthesizes selenophosphate from selenide and ATP. | 0.807 |
SFN54340.1 | thiI | SAMN05421579_1086 | SAMN05421579_13229 | Nitroreductase. | [ThiS-adenylate] sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.471 |
SFN54340.1 | topB | SAMN05421579_1086 | SAMN05421579_1088 | Nitroreductase. | DNA topoisomerase-3; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.780 |
SFN60492.1 | SFN45523.1 | SAMN05421579_11133 | SAMN05421579_10483 | Thioredoxin reductase (NADPH). | Cysteine desulfurase. | 0.660 |
SFN60492.1 | selD | SAMN05421579_11133 | SAMN05421579_1087 | Thioredoxin reductase (NADPH). | Selenophosphate synthase; Synthesizes selenophosphate from selenide and ATP. | 0.605 |
SFN60492.1 | thiI | SAMN05421579_11133 | SAMN05421579_13229 | Thioredoxin reductase (NADPH). | [ThiS-adenylate] sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.594 |
SFN68524.1 | selA | SAMN05421579_11513 | SAMN05421579_11514 | Selenocysteine-specific translation elongation factor SelB. | L-seryl-tRNA(Sec) selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis; Belongs to the SelA family. | 0.948 |
SFN68524.1 | selD | SAMN05421579_11513 | SAMN05421579_1087 | Selenocysteine-specific translation elongation factor SelB. | Selenophosphate synthase; Synthesizes selenophosphate from selenide and ATP. | 0.845 |
SFN84137.1 | iscS | SAMN05421579_12521 | SAMN05421579_11359 | Cysteine desulfurase. | Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | 0.576 |
SFN84137.1 | selD | SAMN05421579_12521 | SAMN05421579_1087 | Cysteine desulfurase. | Selenophosphate synthase; Synthesizes selenophosphate from selenide and ATP. | 0.575 |
SFN84137.1 | thiI | SAMN05421579_12521 | SAMN05421579_13229 | Cysteine desulfurase. | [ThiS-adenylate] sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.954 |
SFO00601.1 | iscS | SAMN05421579_14325 | SAMN05421579_11359 | Cysteine desulfurase. | Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | 0.414 |
SFO00601.1 | selD | SAMN05421579_14325 | SAMN05421579_1087 | Cysteine desulfurase. | Selenophosphate synthase; Synthesizes selenophosphate from selenide and ATP. | 0.650 |
SFO00601.1 | thiI | SAMN05421579_14325 | SAMN05421579_13229 | Cysteine desulfurase. | [ThiS-adenylate] sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.954 |
iscS | SFN84137.1 | SAMN05421579_11359 | SAMN05421579_12521 | Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | Cysteine desulfurase. | 0.576 |
iscS | SFO00601.1 | SAMN05421579_11359 | SAMN05421579_14325 | Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | Cysteine desulfurase. | 0.414 |
iscS | selD | SAMN05421579_11359 | SAMN05421579_1087 | Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | Selenophosphate synthase; Synthesizes selenophosphate from selenide and ATP. | 0.744 |
iscS | thiI | SAMN05421579_11359 | SAMN05421579_13229 | Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | [ThiS-adenylate] sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.954 |