Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
gnd6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (473 aa)    
Predicted Functional Partners:
zwf
Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
 
 0.993
LIU_01600
Gluconate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FGGY kinase family.
  
 
 0.966
LIU_03990
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.958
LIU_02235
Catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family.
   
 0.955
rpiA
Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
   
 
 0.944
LIU_07580
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.864
LIU_03475
Altronate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.800
pyk
Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.794
arlR
PhoB family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.771
LIU_05980
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.748
Your Current Organism:
Enterococcus durans
NCBI taxonomy Id: 53345
Other names: ATCC 19432, CCUG 7972, CIP 55.125, DSM 20633, E. durans, Enterococcus sp. VJI19, JCM 8725, LMG 10746, LMG:10746, NBRC 100479, NCDO 596, NCIMB 700596, NCTC 8307, Streptococcus durans, strain 98D
Server load: low (12%) [HD]