Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LIU_09005Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (90 aa)    
Predicted Functional Partners:
mprF-2
Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
  
    0.876
LIU_09010
Diacylglycerol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.848
LIU_09025
SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.762
pepT
Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.
       0.748
LIU_09020
NGG1p interacting factor NIF3; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
       0.742
Your Current Organism:
Enterococcus durans
NCBI taxonomy Id: 53345
Other names: ATCC 19432, CCUG 7972, CIP 55.125, DSM 20633, E. durans, Enterococcus sp. VJI19, JCM 8725, LMG 10746, LMG:10746, NBRC 100479, NCDO 596, NCIMB 700596, NCTC 8307, Streptococcus durans, strain 98D
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