STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LIU_10285Signal peptidase I; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family. (193 aa)    
Predicted Functional Partners:
LIU_04145
Signal peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family.
 
  
 0.926
LIU_10275
Sortase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.784
LIU_10280
Phosphate-transport permease PitB; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.711
LIU_10290
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.618
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
  
  
 0.603
LIU_10270
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.569
LIU_11165
RNA polymerase factor sigma-54; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.470
nusA
Transcription elongation factor NusA; Participates in both transcription termination and antitermination.
   
    0.414
phoU
PhoU family transcriptional regulator; Plays a role in the regulation of phosphate uptake.
   
    0.414
kduI
5-keto-4-deoxyuronate isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family.
   
    0.412
Your Current Organism:
Enterococcus durans
NCBI taxonomy Id: 53345
Other names: ATCC 19432, CCUG 7972, CIP 55.125, DSM 20633, E. durans, Enterococcus sp. VJI19, JCM 8725, LMG 10746, LMG:10746, NBRC 100479, NCDO 596, NCIMB 700596, NCTC 8307, Streptococcus durans, strain 98D
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.