STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ORA76517.1NADP oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (286 aa)    
Predicted Functional Partners:
fbiB
Coenzyme F420-0:L-glutamate ligase; Bifunctional enzyme that catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives, and the FMNH2- dependent reduction of dehydro-F420-0 to form F420-0. In the N-terminal section; belongs to the CofE family.
 
  
 0.792
ORA76242.1
LLM class F420-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.791
fbiA
2-phospho-L-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.
 
   
 0.774
ORA75490.1
LLM class F420-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.761
fbiD
2-phospho-L-lactate guanylyltransferase; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.
 
   
 0.757
ORA70236.1
LLM class F420-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.753
ORA74798.1
Luciferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.747
ORA76514.1
acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.739
ORA68053.1
Deazaflavin-dependent nitroreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.727
ORA76513.1
feruloyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.726
Your Current Organism:
Mycobacterium heidelbergense
NCBI taxonomy Id: 53376
Other names: ATCC 51253, CIP 105424, DSM 44471, JCM 14842, M. heidelbergense, strain 2554/91
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