STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ORA76222.13-alpha-hydroxysteroid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (275 aa)    
Predicted Functional Partners:
mhpB
3-(2,3-dihydroxyphenyl)propionate dioxygenase; Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3-dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2-hydroxy-6- ketononatrienedioate, respectively; Belongs to the LigB/MhpB extradiol dioxygenase family.
 
  
  0.899
ORA76220.1
Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
  0.896
ORA76221.1
Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.895
ORA76227.1
Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
  0.881
BST25_00135
Hypothetical protein; Frameshifted; internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.878
mhpA
3-(3-hydroxyphenyl)propionate hydroxylase; Catalyzes the insertion of one atom of molecular oxygen into position 2 of the phenyl ring of 3-(3-hydroxyphenyl)propionate (3-HPP) and hydroxycinnamic acid (3HCI).
 
  
  0.860
ORA76223.1
Monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.856
ORA67360.1
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.841
ORA66842.1
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.841
ORA76224.1
3-ketosteroid-delta-1-dehydrogenase; Initiates steroid ring degradation; catalyzes the transhydrogenation of 3-keto-4-ene-steroid to 3-keto-1,4-diene-steroid e.g., progesterone to 1,4-androstadiene-3,17-dione; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.836
Your Current Organism:
Mycobacterium heidelbergense
NCBI taxonomy Id: 53376
Other names: ATCC 51253, CIP 105424, DSM 44471, JCM 14842, M. heidelbergense, strain 2554/91
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.