ORA76353.1 protein (Mycobacterium heidelbergense)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Mycobacterium heidelbergense

NCBI taxonomy Id: 53376
Other names: ATCC 51253, CIP 105424, DSM 44471, JCM 14842, M. heidelbergense, strain 2554/91

Export your current network:

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file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

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same PNG format, but at higher resolution

... as a vector graphic:

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ORA69538.1	ORA76353.1	BST25_21305	BST25_02115	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Trypsin; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.441
ORA76352.1	ORA76353.1	BST25_02110	BST25_02115	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Trypsin; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.467
ORA76353.1	ORA69538.1	BST25_02115	BST25_21305	Trypsin; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.441
ORA76353.1	ORA76352.1	BST25_02115	BST25_02110	Trypsin; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.467
ORA76353.1	ORA76423.1	BST25_02115	BST25_02120	Trypsin; Derived by automated computational analysis using gene prediction method: Protein Homology.	Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.487
ORA76353.1	guaA	BST25_02115	BST25_16000	Trypsin; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.676
ORA76353.1	guaB	BST25_02115	BST25_15965	Trypsin; Derived by automated computational analysis using gene prediction method: Protein Homology.	IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.472
ORA76423.1	ORA76353.1	BST25_02120	BST25_02115	Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Trypsin; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.487
ORA76423.1	guaA	BST25_02120	BST25_16000	Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.431
guaA	ORA76353.1	BST25_16000	BST25_02115	Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP.	Trypsin; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.676
guaA	ORA76423.1	BST25_16000	BST25_02120	Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP.	Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.431
guaA	guaB	BST25_16000	BST25_15965	Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP.	IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.999
guaB	ORA76353.1	BST25_15965	BST25_02115	IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	Trypsin; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.472
guaB	guaA	BST25_15965	BST25_16000	IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.999