STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ORA76406.13-ketosteroid-delta-1-dehydrogenase; Initiates steroid ring degradation; catalyzes the transhydrogenation of 3-keto-4-ene-steroid to 3-keto-1,4-diene-steroid e.g., progesterone to 1,4-androstadiene-3,17-dione; Derived by automated computational analysis using gene prediction method: Protein Homology. (560 aa)    
Predicted Functional Partners:
ORA76398.1
3-ketosteroid-9-alpha-hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.982
ORA74471.1
3-ketosteroid-9-alpha-hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.967
ORA76407.1
3-alpha,7-alpha, 12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.960
ORA70072.1
Succinate dehydrogenase, cytochrome b556 subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.927
kgd
Alpha-ketoglutarate decarboxylase; Kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.905
ORA74443.1
Lipid-transfer protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.899
ORA76396.1
Ketosteroid isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.888
ORA70071.1
Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.872
ORA71276.1
Succinate dehydrogenase/fumarate reductase iron-sulfur subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.865
ORA70069.1
Succinate dehydrogenase iron-sulfur subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.865
Your Current Organism:
Mycobacterium heidelbergense
NCBI taxonomy Id: 53376
Other names: ATCC 51253, CIP 105424, DSM 44471, JCM 14842, M. heidelbergense, strain 2554/91
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