STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ORA75922.1DUF4126 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (160 aa)    
Predicted Functional Partners:
ORA75923.1
Mercuric reductase; Enables the enzymatic reduction of mercuric ions to elemental mercury; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.931
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
       0.642
hisE
phosphoribosyl-ATP diphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.622
ORA72121.1
1,4-beta-xylanase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 5 (cellulase A) family.
  
     0.594
ORA70545.1
PirG; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.513
ORA70413.1
Type VII secretion integral membrane protein EccD; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.509
ORA75666.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.501
ORA72124.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.487
ORA75919.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
       0.470
ORA72260.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.462
Your Current Organism:
Mycobacterium heidelbergense
NCBI taxonomy Id: 53376
Other names: ATCC 51253, CIP 105424, DSM 44471, JCM 14842, M. heidelbergense, strain 2554/91
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