STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ORA75927.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (182 aa)    
Predicted Functional Partners:
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.971
ORA75203.1
ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.959
ORA65394.1
ATPase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 0.930
ORA69996.1
Hypothetical protein; Contains 3'-5'exonuclease domain; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.897
ORA76633.1
DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.885
recA
Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.884
ORA73726.1
Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.880
ORA75939.1
Flap endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.877
dnaA
Chromosomal replication initiation protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
  
 
 0.875
ORA75926.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.865
Your Current Organism:
Mycobacterium heidelbergense
NCBI taxonomy Id: 53376
Other names: ATCC 51253, CIP 105424, DSM 44471, JCM 14842, M. heidelbergense, strain 2554/91
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