STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ORA76065.1Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (245 aa)    
Predicted Functional Partners:
ORA76064.1
AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 
0.918
tpx
Lipid hydroperoxide peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
       0.696
sigA
RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
 
 0.602
ORA75640.1
RNA polymerase subunit sigma; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
   
 
 0.602
lexA
Repressor LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
   
 
 0.475
ORA74231.1
Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.440
ORA71411.1
GNAT family N-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.438
ORA74767.1
DNA-3-methyladenine glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.412
menC
O-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB).
       0.410
ORA73001.1
Bromoperoxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.410
Your Current Organism:
Mycobacterium heidelbergense
NCBI taxonomy Id: 53376
Other names: ATCC 51253, CIP 105424, DSM 44471, JCM 14842, M. heidelbergense, strain 2554/91
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