STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ORA75625.1DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (135 aa)    
Predicted Functional Partners:
ORA75793.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.811
ORA75623.1
DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.747
ORA75624.1
Potassium transporter TrkA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.730
ORA75792.1
Potassium transporter TrkA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.713
ORA75626.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.645
ORA75667.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.615
htpX
Zinc metalloprotease HtpX; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase M48B family.
   
    0.601
ORA75203.1
ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.592
ORA73250.1
TIGR03085 family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.588
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.463
Your Current Organism:
Mycobacterium heidelbergense
NCBI taxonomy Id: 53376
Other names: ATCC 51253, CIP 105424, DSM 44471, JCM 14842, M. heidelbergense, strain 2554/91
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.