STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ORA75663.1Signal transduction histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (68 aa)    
Predicted Functional Partners:
ORA75797.1
Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.881
ORA75664.1
Limonene-1,2-epoxide hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.777
ORA75665.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.725
ORA74823.1
Nuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.538
nucS
Endonuclease; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family.
      
 0.455
whiB-6
WhiB family transcriptional regulator; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
     0.450
crgA
Cell division protein CrgA; Involved in cell division; Belongs to the CrgA family.
  
     0.433
recX
Recombination regulator RecX; Modulates RecA activity; Belongs to the RecX family.
       0.419
ORA72963.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0336 family.
  
     0.402
recA
Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
       0.401
Your Current Organism:
Mycobacterium heidelbergense
NCBI taxonomy Id: 53376
Other names: ATCC 51253, CIP 105424, DSM 44471, JCM 14842, M. heidelbergense, strain 2554/91
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