STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ORA75477.1Cutinase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (248 aa)    
Predicted Functional Partners:
ORA75284.1
Phosphotyrosine protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.861
ORA74379.1
NADH-quinone oxidoreductase subunit M; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.840
ORA75406.1
Transmembrane carbonic anhydrase SulP; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.684
ORA73011.1
Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.684
ORA67786.1
Peptidase S8; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.664
ORA70889.1
Type VII secretion-associated serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.659
ORA70412.1
Type VII secretion-associated serine protease mycosin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.658
ORA73185.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.652
secY
Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
    
   0.652
ORA74006.1
ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  0.631
Your Current Organism:
Mycobacterium heidelbergense
NCBI taxonomy Id: 53376
Other names: ATCC 51253, CIP 105424, DSM 44471, JCM 14842, M. heidelbergense, strain 2554/91
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.