Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ORA75076.1Adenylyltransferase/sulfurtransferase MoeZ; Derived by automated computational analysis using gene prediction method: Protein Homology. (398 aa)    
Predicted Functional Partners:
ORA71151.1
Molybdenum cofactor biosynthesis protein MoaE; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.989
ORA70475.1
Molybdopterin synthase sulfur carrier subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.982
ORA74752.1
Molybdopterin synthase sulfur carrier subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.981
thiG
Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
 
 0.974
ORA72681.1
Cysteine desulfurase NifS; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.969
ORA73707.1
Thiamine biosynthesis protein ThiS; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.949
ORA74753.1
Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.870
ORA67143.1
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
 0.834
thiE
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
 
 0.809
ORA75075.1
TIGR02569 family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.807
Your Current Organism:
Mycobacterium heidelbergense
NCBI taxonomy Id: 53376
Other names: ATCC 51253, CIP 105424, DSM 44471, JCM 14842, M. heidelbergense, strain 2554/91
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