STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ORA74713.1acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (381 aa)    
Predicted Functional Partners:
ORA71128.1
3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.990
BST25_13110
Transposase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.936
ORA75387.1
Acyl dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.926
ORA71144.1
DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.904
ORA74953.1
Nucleic acid-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  0.850
ORA75378.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  0.843
ORA66635.1
acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  0.841
ORA75962.1
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.781
ORA71543.1
benzoylsuccinyl-CoA thiolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.779
acsA
acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.767
Your Current Organism:
Mycobacterium heidelbergense
NCBI taxonomy Id: 53376
Other names: ATCC 51253, CIP 105424, DSM 44471, JCM 14842, M. heidelbergense, strain 2554/91
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.