| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ORA74616.1 | ORA74617.1 | BST25_08550 | BST25_08555 | Arsenate reductase (glutaredoxin); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ArsC family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.867 |
| ORA74616.1 | ORA75473.1 | BST25_08550 | BST25_05110 | Arsenate reductase (glutaredoxin); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ArsC family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.618 |
| ORA74616.1 | ORA76591.1 | BST25_08550 | BST25_00490 | Arsenate reductase (glutaredoxin); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ArsC family. | Disulfide bond formation protein DsbA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.618 |
| ORA74616.1 | folD | BST25_08550 | BST25_19960 | Arsenate reductase (glutaredoxin); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ArsC family. | Bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.519 |
| ORA74616.1 | gcvH | BST25_08550 | BST25_18645 | Arsenate reductase (glutaredoxin); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ArsC family. | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.502 |
| ORA74616.1 | gcvP | BST25_08550 | BST25_18670 | Arsenate reductase (glutaredoxin); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ArsC family. | Glycine dehydrogenase (aminomethyl-transferring); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.749 |
| ORA74616.1 | glmU | BST25_08550 | BST25_08540 | Arsenate reductase (glutaredoxin); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ArsC family. | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.732 |
| ORA74616.1 | prs | BST25_08550 | BST25_08545 | Arsenate reductase (glutaredoxin); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ArsC family. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.869 |
| ORA74616.1 | rpoA | BST25_08550 | BST25_15740 | Arsenate reductase (glutaredoxin); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ArsC family. | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.775 |
| ORA74616.1 | thyA | BST25_08550 | BST25_04380 | Arsenate reductase (glutaredoxin); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ArsC family. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.482 |
| ORA74617.1 | ORA74616.1 | BST25_08555 | BST25_08550 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Arsenate reductase (glutaredoxin); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ArsC family. | 0.867 |
| ORA74617.1 | glmU | BST25_08555 | BST25_08540 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.732 |
| ORA74617.1 | prs | BST25_08555 | BST25_08545 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.867 |
| ORA75473.1 | ORA74616.1 | BST25_05110 | BST25_08550 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Arsenate reductase (glutaredoxin); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ArsC family. | 0.618 |
| ORA76591.1 | ORA74616.1 | BST25_00490 | BST25_08550 | Disulfide bond formation protein DsbA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Arsenate reductase (glutaredoxin); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ArsC family. | 0.618 |
| folD | ORA74616.1 | BST25_19960 | BST25_08550 | Bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Arsenate reductase (glutaredoxin); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ArsC family. | 0.519 |
| folD | gcvH | BST25_19960 | BST25_18645 | Bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.931 |
| folD | gcvP | BST25_19960 | BST25_18670 | Bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Glycine dehydrogenase (aminomethyl-transferring); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.975 |
| folD | thyA | BST25_19960 | BST25_04380 | Bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.916 |
| gcvH | ORA74616.1 | BST25_18645 | BST25_08550 | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Arsenate reductase (glutaredoxin); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ArsC family. | 0.502 |
