Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ORA74687.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (656 aa)    
Predicted Functional Partners:
ORA74688.1
Magnesium chelatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.976
purH
Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.640
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
       0.640
ORA74692.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.570
ORA74689.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.542
ORA75916.1
Phosphatidylinositol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.533
ORA69808.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.427
ORA75914.1
Phosphoglycerate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.409
Your Current Organism:
Mycobacterium heidelbergense
NCBI taxonomy Id: 53376
Other names: ATCC 51253, CIP 105424, DSM 44471, JCM 14842, M. heidelbergense, strain 2554/91
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