Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ORA74420.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (570 aa)    
Predicted Functional Partners:
ORA74333.1
DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.998
ORA69018.1
Stage II sporulation protein E; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.991
ORA73175.1
DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.964
ORA71559.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.963
ORA74695.1
LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.959
ORA74339.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.943
ORA69539.1
Helix-turn-helix transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.911
ORA74871.1
Guanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.893
ORA74646.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.871
ORA76613.1
Adenylate/guanylate cyclase domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.805
Your Current Organism:
Mycobacterium heidelbergense
NCBI taxonomy Id: 53376
Other names: ATCC 51253, CIP 105424, DSM 44471, JCM 14842, M. heidelbergense, strain 2554/91
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