Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ORA71409.1Glyoxalase/bleomycin resistance/dioxygenase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (117 aa)    
Predicted Functional Partners:
ORA75563.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.781
trpA
Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
     
  0.780
trpB
Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
     
  0.780
ilvA
Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
     
  0.780
ORA74878.1
Monoamine oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.604
ORA74366.1
Monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.604
ORA71410.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.577
ORA74287.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.560
ORA69600.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.551
ORA69857.1
TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.524
Your Current Organism:
Mycobacterium heidelbergense
NCBI taxonomy Id: 53376
Other names: ATCC 51253, CIP 105424, DSM 44471, JCM 14842, M. heidelbergense, strain 2554/91
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