STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ORA70771.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (199 aa)    
Predicted Functional Partners:
ORA67360.1
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.849
ORA75962.1
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.819
ORA65394.1
ATPase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
   
 0.811
ORA70772.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.797
ORA76628.1
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.786
BST25_13710
Hypothetical protein; Incomplete; partial in the middle of a contig; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.786
ORA72895.1
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.786
ORA72299.1
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.786
arc
Proteasome ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
    
  0.708
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
    
 0.674
Your Current Organism:
Mycobacterium heidelbergense
NCBI taxonomy Id: 53376
Other names: ATCC 51253, CIP 105424, DSM 44471, JCM 14842, M. heidelbergense, strain 2554/91
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.