| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ORA70319.1 | pyrG | BST25_19435 | BST25_19430 | ADP-ribose pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.986 |
| ORA70319.1 | xerD | BST25_19435 | BST25_19440 | ADP-ribose pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Site-specific tyrosine recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.980 |
| guaA | ndk | BST25_16000 | BST25_00595 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.571 |
| guaA | pyrG | BST25_16000 | BST25_19430 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.978 |
| guaA | rplE | BST25_16000 | BST25_10385 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. | 0.520 |
| guaA | rplF | BST25_16000 | BST25_10370 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 0.403 |
| guaA | rplM | BST25_16000 | BST25_15800 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.800 |
| guaA | rplN | BST25_16000 | BST25_10395 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. | 0.648 |
| guaA | rplW | BST25_16000 | BST25_10490 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. | 0.446 |
| guaA | rpmD | BST25_16000 | BST25_10355 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 50S ribosomal protein L30; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.612 |
| ndk | guaA | BST25_00595 | BST25_16000 | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.571 |
| ndk | pyrG | BST25_00595 | BST25_19430 | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.959 |
| ndk | rplE | BST25_00595 | BST25_10385 | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. | 0.681 |
| ndk | rplF | BST25_00595 | BST25_10370 | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 0.758 |
| ndk | rplM | BST25_00595 | BST25_15800 | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.975 |
| ndk | rplN | BST25_00595 | BST25_10395 | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. | 0.766 |
| ndk | rplW | BST25_00595 | BST25_10490 | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. | 0.637 |
| ndk | rpmD | BST25_00595 | BST25_10355 | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 50S ribosomal protein L30; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.459 |
| pyrG | ORA70319.1 | BST25_19430 | BST25_19435 | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | ADP-ribose pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.986 |
| pyrG | guaA | BST25_19430 | BST25_16000 | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.978 |