STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ORA70065.1RNA polymerase sigma factor SigJ; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. (300 aa)    
Predicted Functional Partners:
ORA74695.1
LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.800
ORA70064.1
Aspartate aminotransferase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
       0.746
ORA74297.1
Mycofactocin system transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.737
ORA71872.1
RNA polymerase subunit sigma; Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in M. tuberculosis this protein regulates polyketide synthases and secreted or membrane proteins; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily.
  
  
 0.721
ORA75706.1
DtxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.718
ORA69942.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.713
ORA75132.1
SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.711
ORA74375.1
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.711
ORA76064.1
AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.703
ORA74612.1
TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.693
Your Current Organism:
Mycobacterium heidelbergense
NCBI taxonomy Id: 53376
Other names: ATCC 51253, CIP 105424, DSM 44471, JCM 14842, M. heidelbergense, strain 2554/91
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.