Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
vapC-15VapC toxin family PIN domain ribonuclease; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (141 aa)    
Predicted Functional Partners:
ORA69786.1
Antitoxin VapB36; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.981
ORA69788.1
enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family.
 
     0.719
vapC-18
VapC toxin family PIN domain ribonuclease; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.
  
   
 0.603
vapC-16
VapC toxin family PIN domain ribonuclease; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.
  
  
 0.587
ORA74644.1
FkbM family methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.571
ORA76003.1
Growth inhibitor PemK; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.532
ORA69785.1
S9 family peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.532
ORA74284.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.529
ORA75991.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.527
ORA69864.1
GNAT family N-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.514
Your Current Organism:
Mycobacterium heidelbergense
NCBI taxonomy Id: 53376
Other names: ATCC 51253, CIP 105424, DSM 44471, JCM 14842, M. heidelbergense, strain 2554/91
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