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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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thiCHydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (630 aa)    
Predicted Functional Partners:
SED45822.1
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase.
 
 
 0.998
thiG
Thiazole-phosphate synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
  
 0.990
thiE
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
 
 0.985
SED19348.1
Sulfur carrier protein ThiS.
  
  
 0.932
SED53124.1
8-oxo-dGTPase.
  
 
 0.893
purM
Phosphoribosylformylglycinamidine cyclo-ligase.
     
 0.876
purK
5-(carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
     
  0.872
SEE01647.1
Adenylyltransferase and sulfurtransferase.
 
  
 0.761
SEC38020.1
ADP-ribose pyrophosphatase.
     
 0.760
SEC37957.1
Hypothetical protein.
       0.749
Your Current Organism:
Pseudomonas anguilliseptica
NCBI taxonomy Id: 53406
Other names: ATCC 33660, CCUG 35503, CIP 106711, DSM 12111, LMG 21629, LMG:21629, P. anguilliseptica
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