| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SED16700.1 | SED16760.1 | SAMN05421553_2153 | SAMN05421553_2154 | Uncharacterized membrane protein. | Protein of unknown function; Manually curated. | 0.675 |
| SED16700.1 | ilvA | SAMN05421553_2153 | SAMN05421553_2152 | Uncharacterized membrane protein. | L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.845 |
| SED16700.1 | rpiA | SAMN05421553_2153 | SAMN05421553_2151 | Uncharacterized membrane protein. | Ribose-5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. | 0.607 |
| SED16760.1 | SED16700.1 | SAMN05421553_2154 | SAMN05421553_2153 | Protein of unknown function; Manually curated. | Uncharacterized membrane protein. | 0.675 |
| SED16760.1 | ilvA | SAMN05421553_2154 | SAMN05421553_2152 | Protein of unknown function; Manually curated. | L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.628 |
| SED16760.1 | rpiA | SAMN05421553_2154 | SAMN05421553_2151 | Protein of unknown function; Manually curated. | Ribose-5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. | 0.436 |
| ilvA | SED16700.1 | SAMN05421553_2152 | SAMN05421553_2153 | L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | Uncharacterized membrane protein. | 0.845 |
| ilvA | SED16760.1 | SAMN05421553_2152 | SAMN05421553_2154 | L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | Protein of unknown function; Manually curated. | 0.628 |
| ilvA | rpiA | SAMN05421553_2152 | SAMN05421553_2151 | L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | Ribose-5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. | 0.781 |
| rpiA | SED16700.1 | SAMN05421553_2151 | SAMN05421553_2153 | Ribose-5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. | Uncharacterized membrane protein. | 0.607 |
| rpiA | SED16760.1 | SAMN05421553_2151 | SAMN05421553_2154 | Ribose-5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. | Protein of unknown function; Manually curated. | 0.436 |
| rpiA | ilvA | SAMN05421553_2151 | SAMN05421553_2152 | Ribose-5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. | L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.781 |
