| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SEC22526.1 | SED17146.1 | SAMN05421553_0523 | SAMN05421553_2161 | L-lactate dehydrogenase (cytochrome). | Hypothetical protein. | 0.529 |
| SEC42405.1 | SED17146.1 | SAMN05421553_0831 | SAMN05421553_2161 | Serine protease DegS. | Hypothetical protein. | 0.411 |
| SED17037.1 | SED17098.1 | SAMN05421553_2159 | SAMN05421553_2160 | Uncharacterized conserved protein, contains NRDE domain. | Hypothetical protein. | 0.875 |
| SED17037.1 | SED17146.1 | SAMN05421553_2159 | SAMN05421553_2161 | Uncharacterized conserved protein, contains NRDE domain. | Hypothetical protein. | 0.745 |
| SED17037.1 | SED17486.1 | SAMN05421553_2159 | SAMN05421553_2167 | Uncharacterized conserved protein, contains NRDE domain. | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.439 |
| SED17037.1 | lgt | SAMN05421553_2159 | SAMN05421553_2162 | Uncharacterized conserved protein, contains NRDE domain. | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | 0.740 |
| SED17037.1 | thyA | SAMN05421553_2159 | SAMN05421553_2163 | Uncharacterized conserved protein, contains NRDE domain. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.740 |
| SED17098.1 | SED17037.1 | SAMN05421553_2160 | SAMN05421553_2159 | Hypothetical protein. | Uncharacterized conserved protein, contains NRDE domain. | 0.875 |
| SED17098.1 | SED17146.1 | SAMN05421553_2160 | SAMN05421553_2161 | Hypothetical protein. | Hypothetical protein. | 0.646 |
| SED17098.1 | lgt | SAMN05421553_2160 | SAMN05421553_2162 | Hypothetical protein. | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | 0.625 |
| SED17098.1 | thyA | SAMN05421553_2160 | SAMN05421553_2163 | Hypothetical protein. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.647 |
| SED17146.1 | SEC22526.1 | SAMN05421553_2161 | SAMN05421553_0523 | Hypothetical protein. | L-lactate dehydrogenase (cytochrome). | 0.529 |
| SED17146.1 | SEC42405.1 | SAMN05421553_2161 | SAMN05421553_0831 | Hypothetical protein. | Serine protease DegS. | 0.411 |
| SED17146.1 | SED17037.1 | SAMN05421553_2161 | SAMN05421553_2159 | Hypothetical protein. | Uncharacterized conserved protein, contains NRDE domain. | 0.745 |
| SED17146.1 | SED17098.1 | SAMN05421553_2161 | SAMN05421553_2160 | Hypothetical protein. | Hypothetical protein. | 0.646 |
| SED17146.1 | SED17486.1 | SAMN05421553_2161 | SAMN05421553_2167 | Hypothetical protein. | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.475 |
| SED17146.1 | SED70636.1 | SAMN05421553_2161 | SAMN05421553_3160 | Hypothetical protein. | Serine protease Do; Belongs to the peptidase S1C family. | 0.411 |
| SED17146.1 | cysG | SAMN05421553_2161 | SAMN05421553_4129 | Hypothetical protein. | uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.464 |
| SED17146.1 | lgt | SAMN05421553_2161 | SAMN05421553_2162 | Hypothetical protein. | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | 0.885 |
| SED17146.1 | thyA | SAMN05421553_2161 | SAMN05421553_2163 | Hypothetical protein. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.868 |
