node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SEC53954.1 | SEE25147.1 | SAMN05421553_1026 | SAMN05421553_4363 | Anthranilate synthase, component II. | Aminodeoxychorismate synthase, subunit I. | 0.999 |
SEC53954.1 | SEE44280.1 | SAMN05421553_1026 | SAMN05421553_4809 | Anthranilate synthase, component II. | Chorismate mutase. | 0.903 |
SEC53954.1 | aroA | SAMN05421553_1026 | SAMN05421553_4807 | Anthranilate synthase, component II. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.903 |
SEC53954.1 | aroB | SAMN05421553_1026 | SAMN05421553_2316 | Anthranilate synthase, component II. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.749 |
SEC53954.1 | aroC | SAMN05421553_1026 | SAMN05421553_3682 | Anthranilate synthase, component II. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.893 |
SEC53954.1 | aroE | SAMN05421553_1026 | SAMN05421553_1560 | Anthranilate synthase, component II. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.901 |
SEC53954.1 | aroK | SAMN05421553_1026 | SAMN05421553_2315 | Anthranilate synthase, component II. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.719 |
SEC53954.1 | trpD | SAMN05421553_1026 | SAMN05421553_1025 | Anthranilate synthase, component II. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.999 |
SEC53954.1 | trpE | SAMN05421553_1026 | SAMN05421553_1027 | Anthranilate synthase, component II. | Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...] | 0.999 |
SEE25147.1 | SEC53954.1 | SAMN05421553_4363 | SAMN05421553_1026 | Aminodeoxychorismate synthase, subunit I. | Anthranilate synthase, component II. | 0.999 |
SEE25147.1 | SEE44280.1 | SAMN05421553_4363 | SAMN05421553_4809 | Aminodeoxychorismate synthase, subunit I. | Chorismate mutase. | 0.877 |
SEE25147.1 | aroA | SAMN05421553_4363 | SAMN05421553_4807 | Aminodeoxychorismate synthase, subunit I. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.802 |
SEE25147.1 | aroB | SAMN05421553_4363 | SAMN05421553_2316 | Aminodeoxychorismate synthase, subunit I. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.503 |
SEE25147.1 | aroC | SAMN05421553_4363 | SAMN05421553_3682 | Aminodeoxychorismate synthase, subunit I. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.889 |
SEE25147.1 | aroE | SAMN05421553_4363 | SAMN05421553_1560 | Aminodeoxychorismate synthase, subunit I. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.783 |
SEE25147.1 | aroK | SAMN05421553_4363 | SAMN05421553_2315 | Aminodeoxychorismate synthase, subunit I. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.639 |
SEE25147.1 | trpD | SAMN05421553_4363 | SAMN05421553_1025 | Aminodeoxychorismate synthase, subunit I. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.995 |
SEE25147.1 | trpE | SAMN05421553_4363 | SAMN05421553_1027 | Aminodeoxychorismate synthase, subunit I. | Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...] | 0.746 |
SEE44280.1 | SEC53954.1 | SAMN05421553_4809 | SAMN05421553_1026 | Chorismate mutase. | Anthranilate synthase, component II. | 0.903 |
SEE44280.1 | SEE25147.1 | SAMN05421553_4809 | SAMN05421553_4363 | Chorismate mutase. | Aminodeoxychorismate synthase, subunit I. | 0.877 |