Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SEE48017.1HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant). (652 aa)    
Predicted Functional Partners:
SEE47872.1
Adenylate cyclase.
 
  
  0.825
ribB
GTP cyclohydrolase II /3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
     
  0.642
SEE45316.1
Adenylate cyclase, class 3.
 
  
  0.586
SED27275.1
HDIG domain-containing protein.
  
     0.562
SEE04909.1
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.534
SEE76508.1
Response regulator receiver modulated diguanylate cyclase.
  
   
 0.525
SEE48043.1
Predicted arabinose efflux permease, MFS family.
       0.516
SED91745.1
Hpt domain-containing protein.
 
    0.483
SEC94999.1
PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein.
 
   
 0.482
SEE47985.1
Transposase, IS4 family /transposase, IS5 family.
       0.480
Your Current Organism:
Pseudomonas anguilliseptica
NCBI taxonomy Id: 53406
Other names: ATCC 33660, CCUG 35503, CIP 106711, DSM 12111, LMG 21629, LMG:21629, P. anguilliseptica
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