STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
iscRHTH-type transcriptional regulator iscR. (142 aa)    
Predicted Functional Partners:
nifS
Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
  
 
 0.928
nifU
NifU-like protein.
 
  
 0.859
iscS
Cysteine desulfurase.
  
 
 0.773
mnmA
tRNA-specific 2-thiouridylase mnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
  
  
 0.673
ywnA_2
Putative HTH-type transcriptional regulator ywnA.
  
     0.610
ctpF
Probable cation-transporting ATPase F.
       0.565
CUM75758.1
Uncharacterised protein.
  
  
 0.565
ytgP_2
Probable cell division protein ytgP.
       0.521
fprA1
H(2)O-forming NADH oxidase.
   
 
 0.411
Your Current Organism:
Blautia hydrogenotrophica
NCBI taxonomy Id: 53443
Other names: B. hydrogenotrophica, DSM 10507, JCM 14656, Ruminococcus hydrogenotrophicus, strain S5a33
Server load: low (14%) [HD]