STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
comMCompetence protein ComM. (507 aa)    
Predicted Functional Partners:
smf
DNA protecting protein DprA.
 
 0.974
CUN01589.1
Uncharacterised protein family UPF0102; Belongs to the UPF0102 family.
 
  
 0.776
CUM82483.1
DNA utilization protein GntX.
 
  
 0.765
topA
DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.693
CUM82676.1
ComEC family competence protein.
 
  
 0.546
codY
Vegetative protein 286B; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family.
       0.537
yxeP_1
Uncharacterized hydrolase YxeP.
  
   0.523
abgB_1
Aminobenzoyl-glutamate utilization protein B; Belongs to the peptidase M20A family.
  
   0.523
abgB_2
Aminobenzoyl-glutamate utilization protein B; Belongs to the peptidase M20A family.
  
   0.523
recJ
Single-stranded-DNA-specific exonuclease recJ.
 
     0.474
Your Current Organism:
Blautia hydrogenotrophica
NCBI taxonomy Id: 53443
Other names: B. hydrogenotrophica, DSM 10507, JCM 14656, Ruminococcus hydrogenotrophicus, strain S5a33
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.