STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PIF1-3ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (639 aa)    
Predicted Functional Partners:
LENED_002083
Origin recognition complex subunit 5.
    
 
 0.809
LENED_000148
DNA replication ATP-dependent helicase Dna2.
    
 
 0.762
LENED_001306
Dna repair and recombination protein rhm52.
    
 
 0.721
LENED_004771
Ras GEF.
   
 
 0.721
LENED_011307
Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.
    
 0.721
LENED_007996
Dna repair protein rad51; Belongs to the RecA family.
   
 
 0.688
LENED_003281
Atp-depentend dna.
  
 
 0.675
LENED_000036
Dsb repair complex subunit.
    
 
 0.660
LENED_004242
Topoisomerase 1-associated factor 1.
    
 
 0.656
LENED_011462
P-loop containing nucleoside triphosphate hydrolase protein.
   
 
 0.647
Your Current Organism:
Lentinula edodes
NCBI taxonomy Id: 5353
Other names: L. edodes, Lentinus edodes, shiitake mushroom
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.