node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FEN1 | LENED_000284 | A0A1Q3ERF1 | A0A1Q3DV64 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Glycosyltransferase family 8 protein. | 0.827 |
FEN1 | LENED_003555 | A0A1Q3ERF1 | A0A1Q3E3X3 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA polymerase subunit delta-2. | 0.972 |
FEN1 | LENED_005370 | A0A1Q3ERF1 | A0A1Q3E8Y0 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA polymerase. | 0.803 |
FEN1 | LENED_005371 | A0A1Q3ERF1 | A0A1Q3E8R9 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA polymerase. | 0.803 |
FEN1 | LENED_005372 | A0A1Q3ERF1 | A0A1Q3E8T4 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA polymerase. | 0.803 |
FEN1 | LENED_007417 | A0A1Q3ERF1 | A0A1Q3EEI4 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA polymerase delta catalytic variant. | 0.983 |
FEN1 | LENED_007471 | A0A1Q3ERF1 | A0A1Q3EEN4 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. | 0.887 |
FEN1 | LENED_007472 | A0A1Q3ERF1 | A0A1Q3EEF7 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. | 0.887 |
FEN1 | LENED_011676 | A0A1Q3ERF1 | A0A1Q3EQN0 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA polymerase; Belongs to the actin family. | 0.983 |
LENED_000284 | FEN1 | A0A1Q3DV64 | A0A1Q3ERF1 | Glycosyltransferase family 8 protein. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.827 |
LENED_000284 | LENED_003555 | A0A1Q3DV64 | A0A1Q3E3X3 | Glycosyltransferase family 8 protein. | DNA polymerase subunit delta-2. | 0.963 |
LENED_000284 | LENED_005370 | A0A1Q3DV64 | A0A1Q3E8Y0 | Glycosyltransferase family 8 protein. | DNA polymerase. | 0.861 |
LENED_000284 | LENED_005371 | A0A1Q3DV64 | A0A1Q3E8R9 | Glycosyltransferase family 8 protein. | DNA polymerase. | 0.861 |
LENED_000284 | LENED_005372 | A0A1Q3DV64 | A0A1Q3E8T4 | Glycosyltransferase family 8 protein. | DNA polymerase. | 0.861 |
LENED_000284 | LENED_007417 | A0A1Q3DV64 | A0A1Q3EEI4 | Glycosyltransferase family 8 protein. | DNA polymerase delta catalytic variant. | 0.937 |
LENED_000284 | LENED_007471 | A0A1Q3DV64 | A0A1Q3EEN4 | Glycosyltransferase family 8 protein. | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. | 0.823 |
LENED_000284 | LENED_007472 | A0A1Q3DV64 | A0A1Q3EEF7 | Glycosyltransferase family 8 protein. | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. | 0.823 |
LENED_000284 | LENED_009064 | A0A1Q3DV64 | A0A1Q3EIQ2 | Glycosyltransferase family 8 protein. | Mitotic spindle checkpoint horma domain-containing protein. | 0.886 |
LENED_000284 | LENED_011676 | A0A1Q3DV64 | A0A1Q3EQN0 | Glycosyltransferase family 8 protein. | DNA polymerase; Belongs to the actin family. | 0.937 |
LENED_003555 | FEN1 | A0A1Q3E3X3 | A0A1Q3ERF1 | DNA polymerase subunit delta-2. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.972 |