LENED_011547 protein (Lentinula edodes) - STRING interaction network

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second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:

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Score

LENED_011547

Serine threonine specific protein phosphatase. (134 aa)

Predicted Functional Partners:

LENED_002368

0.951

LENED_001919

0.945

LENED_005241

0.923

LENED_007339

0.913

LENED_007340

0.913

LENED_000286

0.891

LENED_001982

0.883

LENED_010475

0.880

LENED_008564

0.877

LENED_005411

0.856

Your Current Organism:

Lentinula edodes

NCBI taxonomy Id: 5353
Other names: L. edodes, Lentinus edodes, shiitake mushroom

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LENED_000286	LENED_001919	A0A1Q3DV45	A0A1Q3DZG7	Uncharacterized protein.	Serine threonine protein phosphatase pp2a-associated protein.	0.408
LENED_000286	LENED_007339	A0A1Q3DV45	A0A1Q3EE42	Uncharacterized protein.	Proteophosphoglycan 5.	0.885
LENED_000286	LENED_007340	A0A1Q3DV45	A0A1Q3EE90	Uncharacterized protein.	Proteophosphoglycan 5.	0.885
LENED_000286	LENED_011547	A0A1Q3DV45	A0A1Q3EQB9	Uncharacterized protein.	Serine threonine specific protein phosphatase.	0.891
LENED_001919	LENED_000286	A0A1Q3DZG7	A0A1Q3DV45	Serine threonine protein phosphatase pp2a-associated protein.	Uncharacterized protein.	0.408
LENED_001919	LENED_001982	A0A1Q3DZG7	A0A1Q3DZX9	Serine threonine protein phosphatase pp2a-associated protein.	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	0.547
LENED_001919	LENED_002368	A0A1Q3DZG7	A0A1Q3E0R0	Serine threonine protein phosphatase pp2a-associated protein.	Duf625 domain protein.	0.411
LENED_001919	LENED_005411	A0A1Q3DZG7	A0A1Q3E919	Serine threonine protein phosphatase pp2a-associated protein.	ARM repeat-containing protein.	0.574
LENED_001919	LENED_007339	A0A1Q3DZG7	A0A1Q3EE42	Serine threonine protein phosphatase pp2a-associated protein.	Proteophosphoglycan 5.	0.441
LENED_001919	LENED_007340	A0A1Q3DZG7	A0A1Q3EE90	Serine threonine protein phosphatase pp2a-associated protein.	Proteophosphoglycan 5.	0.441
LENED_001919	LENED_008564	A0A1Q3DZG7	A0A1Q3EHC9	Serine threonine protein phosphatase pp2a-associated protein.	ARM repeat-containing protein.	0.506
LENED_001919	LENED_010475	A0A1Q3DZG7	A0A1Q3EMH5	Serine threonine protein phosphatase pp2a-associated protein.	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.	0.532
LENED_001919	LENED_011547	A0A1Q3DZG7	A0A1Q3EQB9	Serine threonine protein phosphatase pp2a-associated protein.	Serine threonine specific protein phosphatase.	0.945
LENED_001982	LENED_001919	A0A1Q3DZX9	A0A1Q3DZG7	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	Serine threonine protein phosphatase pp2a-associated protein.	0.547
LENED_001982	LENED_005241	A0A1Q3DZX9	A0A1Q3E8H0	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	Serine/threonine-protein kinase.	0.954
LENED_001982	LENED_005411	A0A1Q3DZX9	A0A1Q3E919	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	ARM repeat-containing protein.	0.995
LENED_001982	LENED_008564	A0A1Q3DZX9	A0A1Q3EHC9	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	ARM repeat-containing protein.	0.977
LENED_001982	LENED_010475	A0A1Q3DZX9	A0A1Q3EMH5	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.	0.991
LENED_001982	LENED_011547	A0A1Q3DZX9	A0A1Q3EQB9	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	Serine threonine specific protein phosphatase.	0.883
LENED_002368	LENED_001919	A0A1Q3E0R0	A0A1Q3DZG7	Duf625 domain protein.	Serine threonine protein phosphatase pp2a-associated protein.	0.411

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Network Stats

number of nodes:

11

number of edges:

33

average node degree:

6

avg. local clustering coefficient:

0.74

expected number of edges:

15

PPI enrichment p-value:

3.1e-05

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0015740

C4-dicarboxylate transport

2 of 2

2.9

1.35

0.0036

GO:0006814

Sodium ion transport

2 of 10

2.2

0.92

0.0200

GO:0071702

Organic substance transport

6 of 546

0.94

0.67

0.0062

GO:0006810

Transport

10 of 1502

0.72

0.61

0.00038

GO:0055085

Transmembrane transport

8 of 1208

0.72

0.52

0.0053

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0030246

Carbohydrate binding

3 of 28

1.93

1.12

0.0067

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:16315

Mixed, incl. Bordetella uptake gene, and Protein of unknown function DUF1468

8 of 32

2.3

6.17

2.85e-14

CL:16364

TRAP transporter solute receptor, DctP family, and TRAP transporter large membrane protein DctM

5 of 5

2.9

5.24

1.72e-10

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map02020

Two-component system

8 of 656

0.98

1.01

2.05e-05

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0031317

Tripartite ATP-independent periplasmic transporter complex

6 of 6

2.9

6.67

2.67e-13

GOCC:0009317

acetyl-CoA carboxylase complex

2 of 8

2.3

1.19

0.0062

GOCC:0032991

Protein-containing complex

8 of 1391

0.66

0.48

0.0058

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF06808

Tripartite ATP-independent periplasmic transporter, DctM component

3 of 3

2.9

2.48

3.01e-05

PF04290

Tripartite ATP-independent periplasmic transporters, DctQ component

3 of 3

2.9

2.48

3.01e-05

PF03480

Bacterial extracellular solute-binding protein, family 7

3 of 3

2.9

2.48

3.01e-05

PF00289

Biotin carboxylase, N-terminal domain

2 of 5

2.5

1.16

0.0076

PF00364

Biotin-requiring enzyme

2 of 11

2.16

0.89

0.0226

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR038404

TRAP transporter solute receptor DctP superfamily

3 of 3

2.9

2.26

7.66e-05

IPR018389

TRAP transporter solute receptor DctP

3 of 3

2.9

2.26

7.66e-05

IPR010656

TRAP C4-dicarboxylate transport system permease DctM subunit

3 of 3

2.9

2.26

7.66e-05

IPR007387

TRAP transporter, small membrane protein DctQ

3 of 3

2.9

2.26

7.66e-05

IPR004681

TRAP transporter large membrane protein DctM

3 of 3

2.9

2.26

7.66e-05

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00878

Biotin carboxylase C-terminal domain

2 of 5

2.5

1.25

0.0052

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