STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LENED_012065GTP cyclohydrolase II. (542 aa)    
Predicted Functional Partners:
LENED_003861
Histone lysine methyltransferase set7.
    
 0.901
LENED_008546
Flavo protein.
  
 
 0.672
LENED_008547
Flavo protein.
  
 
 0.672
LENED_002254
Thymidylate synthase.
  
 
 0.655
LENED_000926
S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
  
 
  0.588
LENED_004859
Phosphosulfolactate synthase.
  
 
  0.588
LENED_001837
Nucleoside hydrolase.
    
 0.585
LENED_004895
Uridine nucleosidase.
    
 0.585
LENED_003617
Inosine guanosine and.
    
 0.576
LENED_012842
S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
    
 0.576
Your Current Organism:
Lentinula edodes
NCBI taxonomy Id: 5353
Other names: L. edodes, Lentinus edodes, shiitake mushroom
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.