STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LENED_012441Recq-mediated genome instability protein 1. (491 aa)    
Predicted Functional Partners:
LENED_011462
P-loop containing nucleoside triphosphate hydrolase protein.
    
 0.998
LENED_012906
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
    
 0.992
LENED_006534
Ribonuclease H-like protein.
    
 0.991
LENED_001745
Replication factor-a protein 1.
    
 0.971
LENED_001741
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
    
 0.971
LENED_010504
Acetyl-synthetase.
    
 0.955
LENED_004227
Crossover junction endonuclease MUS81.
    
 0.954
LENED_010221
DNA repair protein rad16.
    
 0.933
LENED_010220
DNA repair protein rad16.
    
 0.933
LENED_007996
Dna repair protein rad51; Belongs to the RecA family.
    
 0.909
Your Current Organism:
Lentinula edodes
NCBI taxonomy Id: 5353
Other names: L. edodes, Lentinus edodes, shiitake mushroom
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.